An architect by training, Florence joined the New York-based architectural firm Kohn Pedersen Fox Associates PC in 2007, before relocating to their Hong Kong in 2008. Since then she has been involved in a series of mixed-use projects, with a special interest on super tall buildings in Asia. Her completed works include Victoria Dockside in Hong Kong, Ping An Finance Center in Shenzhen, as well as CTF Center in Guangzhou.
A licensed architect in both the US and Hong Kong, Chan holds a Master in Architecture from Harvard Graduate School of Design and a Bachelor of Social Science in Architectural Studies from the Chinese University of Hong Kong. In addition to practicing architecture, Chan teaches architectural design at her the Chinese University of Hong Kong. She is a Board member on the Council on Tall Buildings and Urban Habitat (CTBUH) Hong Kong.